Welcome to
Sysmex Flow Cytometry Germany!

For ordering please make sure you are in your local shop.
If you are from Germany then please continue.
Otherwise please go to your country.

Go to my country Continue

CyFlow™ CD21 Purified

CyFlow™ CD21 Purified
Antigen: CD21
Alternative Name: C3dR, CR2, EBV-R
Clone: LT21
Application: Flow cytometry, Immunohistochemistry (frozen sections)
Format/Fluorochrome: Purified
Target Species: Cow, Dog, Human, Pig
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Isotype: IgG1
Order number: BJ686541

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 1 mg/ml Quantity 0.1 mg Volume 0.1 ml Immunogen IM9 human... more
CyFlow™ CD21 Purified
Concentration1 mg/ml
Quantity0.1 mg
Volume0.1 ml
ImmunogenIM9 human B-lymphoblastoid cell line
SpecifityThe mouse monoclonal antibody LT21 recognizes CD21 antigen, a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
Background InformationCD21 (CR2; complement receptor 2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

Article successfully added.