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CyFlow™ CD41 Low Endotoxin

CyFlow™ CD41 Low Endotoxin
Antigen: CD41
Alternative Name: gpIIb
Clone: MWReg30
Application: Enzyme-linked immunosorbent assay, Flow cytometry, Functional assays, Immunohistochemistry, Immunoprecipitation
Format/Fluorochrome: Low Endotoxin
Target Species: Mouse
Field of Interest: Immunophenotyping, MHC
Species of Origin: Rat
Regulatory Status: RUO
Clonality: monoclonal
Isotype: IgG1
Order number: CA478931

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 1 mg/ml Quantity 0.1 mg Volume 0.1 ml Immunogen Murine platelets... more
CyFlow™ CD41 Low Endotoxin
Concentration1 mg/ml
Quantity0.1 mg
Volume0.1 ml
ImmunogenMurine platelets
SpecifityThe rat monoclonal antibody MWReg30 recognizes mouse CD41 antigen, a transmembrane glycoprotein (integrin family) composed of two chains GPIIb α (heavy chain; 120 kDa) and GPIIb β (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Background InformationCD41 (GPIIb; platelet glycoprotein IIb) is composed of two subunits (120 kDa GPIIb α and 23 kDa GPIIb β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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