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CyFlow™ CD46 Purified

CyFlow™ CD46 Purified
Application: Flow cytometry, Immunoprecipitation, Western blot
Clonality: monoclonal
Target Species: Cow, Human
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Isotype: IgG1
Antigen: CD46
Alternative Name: MCP
Clone: MEM-258
Order number: CE973787
150,00  EUR *

Prices net excl. VAT, plus applicable shipping costs

Delivery time appr. 3-5 workdays

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Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Produktinformationen zu: "CyFlow™ CD46 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman Acute Lymphocytic Leukemia (ALL) T cells
Background InformationCD46 (MCP; membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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* All prices are quoted net of the statutory value-added tax and shipping costs and possibly delivery charges, if not otherwise described

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