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CyFlow™ CD85j Purified

CyFlow™ CD85j Purified
Antigen: CD85j
Alternative Name: LIR-1, LIR1 ILT2
Clone: GHI/75
Application: Flow cytometry, Functional assays, Immunoprecipitation, Western blot
Format/Fluorochrome: Purified
Target Species: Human
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Isotype: IgG2b
Order number: AC207504

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Concentration 1 mg/ml Quantity 0.1 mg Volume 0.1 ml Immunogen Hairy cell... more
CyFlow™ CD85j Purified
Concentration1 mg/ml
Quantity0.1 mg
Volume0.1 ml
ImmunogenHairy cell leukaemia cells
SpecifityThe mouse monoclonal antibody GHI/75 recognizes CD85j antigen, an 110-120 kDa membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells, and weakly on monocytes. It is also expressed on T cell and NK cell subsets (variable, individual).
Background InformationCD85j (ILT-2; Ig-like transcript 2, LIR-1; leukocyte Ig-like receptor 1 or LILRB1; leukocyte Ig-like receptor B1) is a member of Ig superfamily transmembrane glycoproteins named CD85. The CD85j protein is expressed on several types of immune cells (plasma cells, B cells, monocytes, T and NK cell subsets) where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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