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CyFlow™ CD1c PE

CyFlow™ CD1c PE
Application: Flow cytometry
Laser: Blue, Green, Yellow
Alternative Name: CD1, R7
Antigen: CD1c
Isotype: IgG1
Emission Maximum: 576 nm
Excitation Maximum: 496 nm, 565 nm
Format/Fluorochrome: PE
Field of Interest: Immunophenotyping
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clonality: monoclonal
Clone: L161
Order number: BG628653
220,00  EUR *

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CD1c (R7, BDCA1) together with CD1a and CD1b, belongs to group 1 of CD1 antigens. These... more
Product information "CyFlow™ CD1c PE"
CD1c (R7, BDCA1) together with CD1a and CD1b, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. CD1c is unique in its ability to present e.g. mycobacterial phosphoketides and polyisoprenoids. CD1c is the only CD1 isoform that has been shown to interact both with α/β and γ/δ T cells.
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