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CyFlow™ CD33 Low Endotoxin

CyFlow™ CD33 Low Endotoxin
Application: Flow cytometry, Functional assays, Immunocytochemistry, Immunohistochemistry (frozen sections), Immunoprecipitation, Western blot
Target Species: Human, Non-Human Primates
Alternative Name: p67, SIGLECT-3
Antigen: CD33
Format/Fluorochrome: Low Endotoxin
Clonality: monoclonal
Isotype: IgG1
Field of Interest: Immunophenotyping
Source Species: Mouse
Regulatory Status: RUO
Clone: WM53
Order number: BX615351
140,00  EUR *

Prices net excl. VAT, plus applicable shipping costs

Delivery time appr. 3-5 workdays

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For Research Use Only
Not for use in diagnostic or therapeutic procedures.

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Beschreibung TDS & SDS
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HLDA Workshop HLDA IV—WS Code M-505 Concentration Unit mg/mL Concentration 1... more
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Produktinformationen zu: "CyFlow™ CD33 Low Endotoxin"
HLDA WorkshopHLDA IV—WS Code M-505
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman Acute Myelogenous Leukemia (AML) cells
Background InformationCD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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* All prices are quoted net of the statutory value-added tax and shipping costs and possibly delivery charges, if not otherwise described

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