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CyFlow™ CD45RA PE
Application: | Flow cytometry |
Laser: | Blue, Green, Yellow |
Alternative Name: | Leu18 |
Antigen: | CD45RA |
Field of Interest: | Immunophenotyping, Phosphorylation |
Emission Maximum: | 576 nm |
Excitation Maximum: | 496 nm, 565 nm |
Format/Fluorochrome: | PE |
Clonality: | monoclonal |
Source Species: | Mouse |
Isotype: | IgG2b |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | MEM-56 |
Order number: | AY553862 |
220,00 EUR *
Prices net excl. VAT, plus applicable shipping costs
Delivery time appr. 3-5 workdays
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA IV—WS Code NL 907 Quantity 100 tests Volume 2.0 mL Immunogen... more
Produktinformationen zu: "CyFlow™ CD45RA PE"
HLDA Workshop | HLDA IV—WS Code NL 907 |
Quantity | 100 tests |
Volume | 2.0 mL |
Immunogen | Human thymocytes and T lymphocytes |
Background Information | CD45RA (Leu18) is a high molecular weight isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RA is expressed e.g. on naive T cells and normal plasma cells. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
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