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CyFlow™ CD27 APC
Application: | Flow cytometry |
Emission Maximum: | 660 nm |
Alternative Name: | S152, T14, TNFRSF7, TP55 |
Antigen: | CD27 |
Isotype: | IgG2a |
Excitation Maximum: | 650 nm |
Clonality: | monoclonal |
Laser: | Red |
Format/Fluorochrome: | APC |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | LT27 |
Order number: | CH238908 |
245,00 EUR *
Prices net excl. VAT, plus applicable shipping costs
Delivery time appr. 3-5 workdays
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA V—WS Code T T-CD27.01 Quantity 100 tests Volume 1.0 mL... more
Produktinformationen zu: "CyFlow™ CD27 APC"
HLDA Workshop | HLDA V—WS Code T T-CD27.01 |
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Human peripheral blood lymphocytes |
Background Information | CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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