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CyFlow™ CD27 Purified
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Target Species: | Human |
| Regulatory Status: | RUO |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping |
| Format/Fluorochrome: | Purified |
| Isotype: | IgG2a |
| Antigen: | CD27 |
| Alternative Name: | S152, T14, TNFRSF7, TP55 |
| Clone: | LT27 |
| Order number: | CY176848 |
140,00 EUR *
Prices net excl. VAT, plus applicable shipping costs
Delivery time appr. 3-5 workdays
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA V—WS Code T T-CD27.01 Concentration Unit mg/mL Concentration 1... more
Produktinformationen zu: "CyFlow™ CD27 Purified"
| HLDA Workshop | HLDA V—WS Code T T-CD27.01 |
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Human peripheral blood lymphocytes |
| Background Information | CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70. |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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